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Showing posts from October, 2011

FDA Approves Onfi

The U.S. Food and Drug Administration (FDA) has approved Onfi (clobazam), an oral benzodiazepine antiepileptic drug, as adjunctive therapy for seizures associated with Lennox-Gastaut syndrome (LGS) in patients two years and older.

what do you know about: Fournier’s gangrene

Fournier’s gangrene is an aggressive and rapidly spreading infection of soft tissue, or necrotizing fasciitis, that involves the deep and superficial fascia of the perineum.1 The rate of fascial necrosis in Fournier’s gangrene is reported to be 2 to 3 cm/h.1 Thrombosis of subcutaneous and cutaneous blood vessels produces gangrene, but the fascial necrosis is usually more extensive than the visible gangrene suggests.2 Classic findings are necrosis of the superficial and deep fascial planes, fibrinoid coagulation of the nutrient arterioles, polymorphonuclear cell infiltration, and positive microorganism culture of involved tissues.

Misadministration of IV Insulin Associated With Dose Measurement and Hyperkalemia Treatment

Problem: We are aware of numerous reports of serious errors associated with the misadministration of insulin. These events have involved various types of practitioners, including physician house officers (HO), nurses, and a pharmacist. Human error (e.g., mental slips, lapses, forgetfulness)

FDA Approves Ferriprox

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October 14, 2011 -- The U.S. Food and Drug Administration today approved Ferriprox (deferiprone) to treat patients with iron overload due to blood transfusions in patients with thalassemia, a genetic blood disorder that causes anemia, who had an inadequate response to prior chelation therapy.

A current list of medications that require refrigeration

Although not a complete list, below you’ll find a list of the most common medications that require refrigeration.     * • Actimmune® (interferon gamma 1B)     * • Benzamycin® (erythromycin/benzoyl peroxide)--gel     * • Benzaclin® (clindamycin/benzoyl peroxide)--gel     * • Betaseron® (interferon beta 1B)--vials

Plavix and PPIs bad company

Detailed View: Safety Labeling Changes Approved By FDA Center for Drug Evaluation and Research (CDER) – August 2010 and February 2011 WARNINGS and PRECAUTIONS Diminished Antiplatelet Activity Due to Impaired CYP2C19 Function

Symptoms in the Pharmacy : skin disorders 2

Eczema and dermatitis Treatment timescale   Most cases of mild to moderate atopic eczema, irritant and allergic dermatitis should respond to skin care and treatment with OTC products. If no improvement has been noted after 1 week, referral to the doctor is advisable.

Symptoms in the Pharmacy : skin disorders 1

Eczema/dermatitis Eczema is a term used synonymously with dermatitis. The latter is more commonly used when an external precipitating factor is present (contact dermatitis). The rashes produced have similar features but the distribution on the body varies and can be diagnostic. Atopic eczema affects up to 20% of children, in many of whom it disappears or greatly improves with age such that 2–10% of adults are affected.