Nuclear Pharmacy
Typical Day at a Nuclear  Pharmacy
Most pharmacies will typically  have between 1 – 3 set “runs”. I’ll explain a typical day at a pharmacy,  just so you get an idea of how the process goes. The night pharmacist  comes in at around midnight and takes any new orders off of the  recording. They will then begin to hit the generators and start  compounding the first run. Technicians and drivers will begin to trickle  in; doses are drawn (including FDG brought in from a cyclotron) and  packed up. First run is out the door and on its way to customers between  03:00 – 05:00. The pharmacist and technicians then have some down time  to clean up, log all of the kits prepared during the run into the  computer, grab a bite to eat, etc. 2nd run then starts at around 06:00; a  second pharmacist arrives at around 07:00 as this is when the phones  start to pick up with same day add-ons from the customers. 2nd run is  out the door by 08:00. A third and fourth pharmacist arrive at 08:30.  One of them will generally be designated to work on the bloods; another  will help answer the phone, take orders, deal with customer service  issues, etc. 3rd run compounding (which is usually pretty light), begins  at 10:00 and is out the door by 11:30. I-131 capsules will need to be  compounded at some point as well. Throughout the day, we’ll field phone  calls ranging from STAT add-ons to clinical questions (i.e. pediatric  dosing, altered biodistribution, questions about drug selection, etc.).  The rest of the day is generally spent setting up for the next night:  order entry, drawing any doses (i.e. Thallium, which has a long  half-life) that can be drawn the day prior. Scripts are printed,  double-checked and any products needed for the next day are ordered. So,  as you can see, the daytime hours are generally spent getting ready for  the following night. The last pharmacist locks up sometime around 17:00  and is on call for the remainder of the night.
Radiation Safety
This is always one of the main  concerns/questions people ask me about nuclear pharmacy (and rightly  so). Radiation safety and proper handling of all RAM is at the forefront  of the training you receive. Employees are required to wear ring badges  on each hand (to monitor extremity exposure) as well as a body badge at  collar/thyroid level (to monitor whole body exposure). Rings are  monitored weekly, and badges monthly, to assess each employee’s  radiation exposure. The US government has set limits (i.e. 5 REM/year  for whole body exposure, 50 REM/year for extremities, etc.). In  addition, companies will oftentimes have even stricter limits than  these, and will assess each individual as necessary if their exposure  approaches action levels. Most of the times, this will entail adjusting  ones compounding techniques to ensure practice of “ALARA” principles.  Each pharmacy will also have a “Radiation safety officer” (who may or  may not be a pharmacist), and they are responsible for overall safety at  the pharmacy: monitoring air concentrations, training personnel, and  keeping employees under all federal/company radiation guidelines.  Pregnant women can officially declare their pregnancy to the company as  well, and will receive an additional fetal badge to be worn near the  belly. She will have even stricter limitations to restrict the amount of  radiation exposed to the child.
Advantages of Becoming a  Nuclear Pharmacist: 
It’s a very specialized field  and there’s a general appreciation for the training/education that  you’ve put in. Salary is very good (generally comparable to retail).  There’s no insurance to deal with, since the hospital/clinic is  responsible for billing the patient. As you saw in my description of a  typical day, (barring any problems), the pace is generally pretty  relaxed and you’ve got some lag time, especially at night. There’s no  dealing with the general public (although this can also be seen as a  disadvantage to some people). You become very close with your staff  (technicians, drivers, admins). You also get to know your customers very  well over the phone; I’ve become good friends with many of the nuclear  pharmacy techs and physicians too. You are treated as a professional and  they value your input and services. After you’ve gotten enough hours  under your belt, you’re also able to become board certified (BCNP) if you so desire; nuclear pharmacy was the  first specialty area established by the BPS. There’s definitely  opportunity for job growth through management, etc. Nuclear is a neat  balance between clinical pharmacy, physics, chemistry, math, management,  business/sales, customer service, issues like <797>; there’s a  little bit of everything for everyone.
Disadvantages of Becoming  a Nuclear Pharmacist: 
The reality is, you are dealing  with radiation and biohazardous material (i.e. blood). You are however,  provided with the training for how to deal with this properly, and it’s  in your own interest to do things by the book. Over-night hours are  another stickler for some people. A fully staffed pharmacy though, will  permit pharmacists to rotate their hours. It may be possible that you  will only have to work the opening shift one week out of every two?  four? six weeks?..depending on the needs of the pharmacy. Specializing  in nuclear also requires you to keep up with “regular” pharmacy.  Hospital/retail pharmacists don’t exactly know what Cardiolite® is, but  nuclear pharmacists rarely talk about the new factor Xa inhibitor  anticoagulant either. I’ve also been asked whether it’s difficult to  find a job as a nuclear pharmacist. The answer is: no…it’s not hard to  find “a” job; you’re a well-trained specialist and there will always be a  demand for you...however, unlike retail pharmacies, you’re not exactly  going to find a nuclear pharmacy on every corner. As a result, it may  take a little longer to find “the” opening you want, in the specific  city/state you’re interested in.
So…if you’ve actually gotten  through all of this, I’m highly impressed! And you’ll have a better  understanding of what nuclear pharmacy is relative to 99.9% of the  general public...because if I tell anyone that I’m a nuclear pharmacist,  I generally just get a blank stare of bewilderment. If you’re even  remotely interested in the field, I highly suggest taking an elective at  your school if one’s offered, sign up for a nuclear rotation, or even  contact a nearby pharmacy to shadow someone for a day. I know the ID  guys are going to jump on me for this one, but generally speaking...and  excluding empiric therapy, you can’t treat a patient unless you know  what you have on your hands. I love that nuclear medicine is able to  provide some of those answers, and provide some interesting treatment  options to patients. It’s an exciting area to practice in!
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