Pharmacology Refresh Cards: Noradrenaline - Norepinephrine
Noradrenaline - norepinephrine Drug name Sympathomimetic (Vasopressor) Group Stimulates alpha-receptors in arterial and venous beds and beta 1 receptors of heart, resulting in peripheral vasoconstriction and stimulation of heart rate and contractility. Coronary vasodilation occurs secondary to enhanced myocardial contractility. Mechanism of action duration Interval dose Uses Cont. infusion 0.01–0.4 µg/kg/min IV infusion via a central vein Septic shock ,with low SVR Severe hypertension may occur if noradrenaline is given to patients taking tricyclic antidepressants since tricyclics block the uptake of noradrenaline into nerve endings. Drug interaction Bradycardia Hypertension Arrhythmias Myocardial ischaemia peripheral ischaemia Side effects Hypovolaemic ...