How to interpret laboratory data:CBC -1
Decrease
|
Increase
|
Normal ranges
|
CBC item
|
|
SI
|
Conventional
|
|||
anemia of all
types, particularly iron deficiency anemia
blood loss,
hemolysis,
pregnancy,
Fluid
replacement increased fluid intake.
|
polycythemia
vera
chronic
obstructive
lung disease
chronic smokers
regular
vigorous exercise
Live at high altitudes.
|
8.7-11.2 mmol/L
7.4-9.9 mmol/L
|
Male: 14-18g/dl
Female: 12-16g/dl
|
Hemoglobin(Hgb)
carrying compound
|
all types of
anemias, blood loss,
hemolysis,
pregnancy,
cirrhosis, hyperthyroidism,
leukemia
|
Same as Hgb
Dehydration
Shock
|
0.39-0.50
0.33-0.45
|
Male: 39%-50%
Female: 33%-45%
|
Hematocrit (Hct)
= (packed cell
volume (PCV))
the volume of
blood that is occupied by RBCs
|
Anemias, lymphomas,
leukemia.
After puberty, females have lower
RBCs and Hgb due to menstrual
bleeding.
|
Erythrocytosis
Polycythemia vera, high altitudes
strenuous exercise
|
4.2-5.9 × 1012
cells/L
3.5-5.5 × 1012
cells/L
|
Male: 4.2-5.9 × 106 cells/mm3
Female: 3.5-5.5 × 106 cells/mm3
|
Red Blood Cell
serve to transport oxygen from the
lungs to the body tissue
|
Microcytic
iron deficiency anemia,
hemolytic anemia,
lead
poisoning, thalassemia
|
Macrocytic
folate deficiency, vitamin B12
deficiency,
alcoholism,
chronic liver disease,
hypothyroidism, anorexia,
use of medications
such as
valproic acid
zidovudine
stavudine antimetabolites
|
76-100 fL
|
76-100 μm3/cell
|
Mean Cell Volume(MCV)
The
average volume of the erythrocyte
|
Hypochromic
iron
deficiency anemia
|
Hyperchromic
folate or vitamin B12 deficiency.
In hyperlipidemia
patients,
falsely
elevated in specimen turbidity
|
26-34 pg/cell
|
26-34 pg/cell
|
Mean Cell Hemoglobin(MCH)
the
average weight of hemoglobin in the RBC
|
iron deficiency anemia, hemolytic
anemia,
lead poisoning, Thalassemia
|
hereditary spherocytosis
hemolytic disorder with marked heterogeneity of clinical features,
ranging from an asymptomatic condition to fulminant hemolytic anemia.
|
320-370 g/L
|
32-37 g/dL
|
Mean Cell Hemoglobin Concentration(MCHC)
average
hemoglobin concentration in the RBC
|
Reticulocytopenia
infectious
causes, alcoholism,
renal disease
(from decreased erythropoietin),
toxins,
untreated iron deficiency
Anemia,
Drug-induced bone marrow suppression
|
Reticulocytosis
Hemolytic anemia,
hemorrhage,
Sickle cell
disease.
Indicative of
response to treatment of anemias secondary to iron, vitamin B12,or folate
deficiency.
|
0.001-0.025 RBC
|
0.1%-2.5% of RBC
|
Reticulocytes
Immature RBCs formed in the bone marrow.
|
Comments