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Ebola virus disease (EVD), better known in past as viral hemorrhagic fever, could be a severe, typically fatal human disease. The Ebola virus causes an acute, serious illness, which is commonly fatal if untreated. Ebola virus disease (EVD) first appeared in 1976 in a pair of coinciding outbreaks, one in Nzara, Sudan, and the other in Yambuku, Democratic Republic of Congo. The latter occurred in an exceedingly village close to the Ebola river, which it takes its name.

Noradrenaline  -  norepinephrine Drug name Sympathomimetic   (Vasopressor) Group Stimulates alpha-receptors in arterial and venous beds and beta 1 receptors of heart, resulting in peripheral vasoconstriction and stimulation of heart rate and contractility. Coronary vasodilation occurs secondary to enhanced myocardial contractility. Mechanism of action duration Interval dose Uses Cont. infusion 0.01–0.4 µg/kg/min IV infusion via a central vein           Septic shock ,with low SVR Severe hypertension may occur if noradrenaline is given to patients taking tricyclic antidepressants since tricyclics block the uptake of noradrenaline into nerve endings. Drug interaction Bradycardia Hypertension Arrhythmias Myocardial ischaemia peripheral ischaemia Side effects Hypovolaemic ...

Ph D: Neven Mohamed For many years, calcium-containing phosphate binders (calcium acetate and calcium carbonate) were considered the best choice in the treatment of hyperphosphatemia, due to they are effective, possessed only moderate side-effects and suppressed parathormone levels with the intention of counteracting progression of secondary hyperparathyroidism. In two head-to-head observational studies (CARE, ARNOS), calcium-containing binders showed signals of clinical superiority versus the comparator sevelamer-HCl. [1.2]   Nevertheless, calcium may be absorbed significantly, which may result in a positive calcium balance and actively contribute progressive cardiovascular and soft-tissue calcification in patients at risk. [3]