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Showing posts from March, 2013

Pharmacy Examining Board of Canada Examination Dates 2013

Schedule of Examinations for Pharmacists Examination Name Examination Date Application Deadline Date* Spring Pharmacist Qualifying Examination MCQ:   May 21 & 22, 2013 Fri. March 1, 2013 OSCE:  Sun. May 26, 2013 Summer Pharmacist Evaluating Examination July 3 & 4, 2013 Fri. April 5, 2013 Fall Pharmacist Qualifying Examination MCQ:   Nov. 6 & 7, 2013 Wed. August 7, 2013 OSCE:   Sat. Nov. 9, 2013 Winter Pharmacist Evaluating Examination January 8 & 9, 2014 Fri. October 4, 2013 * Applications must be RECEIVED by the PEBC office no later than the application deadline date.

High-Dose Statins Linked to Acute Kidney Damage

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TUESDAY March 19, 2013 --  People who take high doses of popular cholesterol-lowering drugs called statins may be more likely to develop kidney problems, a new study suggests. Specifically, those participants who took higher doses of statins were 34 percent more likely to be hospitalized for acute kidney injury during the first 120 days of treatment, compared to their counterparts who were taking lower doses. This risk remained elevated two years after starting treatment. The findings appeared online March 19 in the journal  BMJ .

FDA Drug Safety Communication: Azithromycin (Zithromax or Zmax) and the risk of potentially fatal heart rhythms

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[3-12-2013]     The U.S. Food and Drug Administration (FDA) is warning the public that azithromycin (Zithromax or Zmax) can cause abnormal changes in the electrical activity of the heart that may lead to a potentially fatal irregular heart rhythm.

Drug-Induced Lupus Erythematosus

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DILE may be induced by medications or caused by other compounds in the environment.  The most common drugs that cause drug-induced SLE are         hydralazine (rate roughly 20%),         procainamide (rate roughly 20%, 5-8% if taken for 1 y),         quinidine,        isoniazid,         minocycline.

Principal causes and the underlying mechanisms of drug-induced hypernatraemia

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A. Water loss 1. Renal losses (i) Acquired nephrogenic diabetes insipidus   Drug-induced hypokalaemia: diuretics, cisplatin, aminoglycosides,   amphotericin B, penicillin derivatives   Drug-induced hypercalcaemia: lithium, vitamin A or D excess   Other drugs: lithium, demeclocycline, amphotericin B, foscarnet,    colchicine, vinblastine, vasopressin V 2 -receptor antagonists

Drugs Induced Thrombocytopenia

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     Immune thrombocytopenia (ITP)  is the commonest blood disorder that causes thrombocytopenia or low platelet count. Apart from ITP, many drugs can cause thrombocytopenia. Some drugs like anticancer drugs and valproic acid cause dose depended decrease in the number of platelets by myelosuppression. Drugs may also cause thrombocytopenia by immunological mechanisms. Immunological drug-induced thrombocytopenia can be caused by the following two mechanisms.

Drug-Induced Hyperkalemia

Certain medications can also make it harder for your kidneys to remove potassium. This is particularly true if you have kidney disease or problems with the way your body handles potassium. Some medications may increase the amount of potassium in the body.